Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners
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Cardiovascular
Biomarker-estimated flavan-3-ol intake is associated with lower blood pressure in cross-sectional analysis in EPIC Norfolk
Absorption & Metabolism
Evaluation of (−)-epicatechin metabolites as recovery biomarker of dietary flavan-3-ol intake
Absorption & Metabolism
Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies
Biological Effects
Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies
Biological Effects
The metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives
Biological Effects
Vasculoprotective Effects of Dietary Cocoa Flavanols in Patients on Hemodialysis: A Double–Blind, Randomized, Placebo–Controlled Trial
Biological Effects
Safety And Efficacy of Cocoa Flavanol Intake In Healthy Adults: A Randomized, Controlled, Double-masked Trial
Cardiovascular
Impact of Cocoa Flavanol Intake On Age-Dependent Vascular Stiffness In Healthy Men: A Randomized, Controlled, Double-masked Trial
Biological Effects
Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study.
Biological Effects
Selective removal of the violet color produced by anthocyanins in procyanidin-rich unfermented cocoa extracts.
Biological Effects
Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity.
Biological Effects
Dimeric procyanidins are inhibitors of NF-kappaB-DNA binding.
Biological Effects
Cytotoxic effects of digalloyl dimer procyanidins in human cancer cell lines.
Biological Effects
Effect of cocoa flavanols and exercise on cardiometabolic risk factors in overweight and obese subjects.
Biological Effects
Sustained benefits in vascular function through flavanol-containing cocoa in medicated diabetic patients a double-masked, randomized, controlled trial.