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Published research

Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners

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Analytical Methods

Reliable, accessible and transferable method for the quantification of flavanols and procyanidins in foodstuffs and dietary supplements†
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Royal Society of Chemistry logo View Abstract
Chemistry

Total Synthesis of Proanthocyanidin A1, A2, and Their Stereoisomers
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Organic Letters logo View Abstract
Chemistry

Enantioselective synthesis of orthogonally protected (2R,3R)-(−)-epicatechin derivatives, key intermediates in the de novo chemical synthesis of (−)-epicatechin glucuronides and sulfates.
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Tetrahedron Letters logo View Abstract
Analytical Methods

Chemical Synthesis and Characterization of Epicatechin Glucuronides and Sulfates: Bioanalytical Standards for Epicatechin Metabolite Identification
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Chemistry

A versatile approach to the regioselective synthesis of diverse (−)-epicatechin-β-D-glucuronides
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Tetrahedron Letters logo View Abstract
Cardiovascular

Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans.
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The American Journal of Clinical Nutrition logo View Abstract
Analytical Methods

Structurally related (-)-epicatechin metabolites in humans: assessment using de novo chemically synthesized authentic standards.
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Analytical Methods

Physicochemical properties of acidified skim milk gels containing cocoa flavanols.
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Journal of Agriculture and Food Chemistry logo View Abstract
Chemistry

The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo.
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Chemistry

Enantioselective syntheses of sulfur analogues of flavan-3-Ols.
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Molecules logo View Abstract
Chemistry

Synthesis of [2-13C, 4-13C]-(2R,3S)-catechin and [2-13C, 4-13C]-(2R,3R)-epicatechin
Journal of Labelled Compounds and Radiopharmaceuticals logo View Abstract
Chemistry

TNFalpha-induced NF-kappaB activation and cell oxidant production are modulated by hexameric procyanidins in Caco-2 cells.
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Archives of Biochemistry and Biophysics logo View Abstract
Analytical Methods

Cocoa flavanols - measurement, bioavailability and bioactivity.
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Cardiovascular

Inhibitory effects of procyanidin B(2) dimer on lipid-laden macrophage formation.
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Journal of Cardiovascular Pharmacology logo View Abstract
Cardiovascular

(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans.
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Proceedings of the National Academy of Sciences of the USA logo View Abstract