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Chemistry

Enantioselective syntheses of sulfur analogues of flavan-3-Ols.
Chemistry

Synthesis of [2-13C, 4-13C]-(2R,3S)-catechin and [2-13C, 4-13C]-(2R,3R)-epicatechin
Cardiovascular

Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease.
Cardiovascular

Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease.
Cardiovascular

Impact of cocoa flavanol consumption on blood pressure responsiveness to exercise.
Biological Effects

Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity.
Biological Effects

Dimeric procyanidins are inhibitors of NF-kappaB-DNA binding.
Analytical Methods

Method performance and multi-laboratory assessment of a normal phase high pressure liquid chromatography-fluorescence detection method for the quantitation of flavanols and procyanidins in cocoa and chocolate containing samples.
Microbiome

Cocoa flavanols and procyanidins can modulate the lipopolysaccharide activation of polymorphonuclear cells in vitro.
Biological Effects

Cytotoxic effects of digalloyl dimer procyanidins in human cancer cell lines.
Chemistry

TNFalpha-induced NF-kappaB activation and cell oxidant production are modulated by hexameric procyanidins in Caco-2 cells.
Cardiovascular

Cocoa flavanols lower vascular arginase activity in human endothelial cells in vitro and in erythrocytes in vivo.
Biological Effects

Effect of cocoa flavanols and exercise on cardiometabolic risk factors in overweight and obese subjects.
Biological Effects

Sustained benefits in vascular function through flavanol-containing cocoa in medicated diabetic patients a double-masked, randomized, controlled trial.
Biological Effects

Selective cytotoxicity of synthesized procyanidin 3-O-galloylepicatechin-4b, 8-3-O-galloylcatechin to human cancer cells.