Published research
Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners
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Biological Effects
Cytotoxic effects of digalloyl dimer procyanidins in human cancer cell lines.
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Cardiovascular
Cocoa flavanols lower vascular arginase activity in human endothelial cells in vitro and in erythrocytes in vivo.
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Biological Effects
Effect of cocoa flavanols and exercise on cardiometabolic risk factors in overweight and obese subjects.
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Biological Effects
Sustained benefits in vascular function through flavanol-containing cocoa in medicated diabetic patients a double-masked, randomized, controlled trial.
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Biological Effects
Selective cytotoxicity of synthesized procyanidin 3-O-galloylepicatechin-4b, 8-3-O-galloylcatechin to human cancer cells.
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Biological Effects
Dimeric procyanidin B2 inhibits constitutively active NF-kappaB in Hodgkin's lymphoma cells independently of the presence of IkappaB mutations.
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Biological Effects
Cerebral blood flow response to flavanol-rich cocoa in healthy elderly humans.
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Analytical Methods
Cocoa flavanols - measurement, bioavailability and bioactivity.
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Brain/Cognitive Health
Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice.
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Cardiovascular
Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week.
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Microbiome
Immune effects of cocoa procyanidin oligomers on peripheral blood mononuclear cells.
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