Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners
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Biological Effects
Selective cytotoxicity of synthesized procyanidin 3-O-galloylepicatechin-4b, 8-3-O-galloylcatechin to human cancer cells.
Microbiome
Flavanol monomer-induced changes to the human faecal microflora.
Biological Effects
Dimeric procyanidin B2 inhibits constitutively active NF-kappaB in Hodgkin's lymphoma cells independently of the presence of IkappaB mutations.
Biological Effects
Daily consumption of a dark chocolate containing flavanols and added sterol esters affects cardiovascular risk factors in a normotensive population with elevated cholesterol.
Biological Effects
Cerebral blood flow response to flavanol-rich cocoa in healthy elderly humans.
Reviews
Effects of cocoa flavanols on risk factors for cardiovascular disease.
Analytical Methods
Cocoa flavanols - measurement, bioavailability and bioactivity.
Brain/Cognitive Health
Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice.
Cardiovascular
Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week.
Microbiome
Immune effects of cocoa procyanidin oligomers on peripheral blood mononuclear cells.
Biological Effects
Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin.
Cardiovascular
Does flavanol intake influence mortality from nitric oxide-dependent processes? Ischemic heart disease, stroke, diabetes mellitus, and cancer in Panama.
Biological Effects
Cocoa flavanol-enriched snack bars containing phytosterols effectively lower total and low-density lipoprotein cholester
Cardiovascular
Procyanidins protect Caco-2 cells from bile acid- and oxidant-induced damage.
Cardiovascular
Inhibitory effects of procyanidin B(2) dimer on lipid-laden macrophage formation.