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Published research

Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners

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Biological Effects

Sustained benefits in vascular function through flavanol-containing cocoa in medicated diabetic patients a double-masked, randomized, controlled trial.
Biological Effects

Selective cytotoxicity of synthesized procyanidin 3-O-galloylepicatechin-4b, 8-3-O-galloylcatechin to human cancer cells.
Microbiome

Flavanol monomer-induced changes to the human faecal microflora.
Biological Effects

Dimeric procyanidin B2 inhibits constitutively active NF-kappaB in Hodgkin's lymphoma cells independently of the presence of IkappaB mutations.
Biological Effects

Daily consumption of a dark chocolate containing flavanols and added sterol esters affects cardiovascular risk factors in a normotensive population with elevated cholesterol.
Biological Effects

Cerebral blood flow response to flavanol-rich cocoa in healthy elderly humans.
Reviews

Effects of cocoa flavanols on risk factors for cardiovascular disease.
Analytical Methods

Cocoa flavanols - measurement, bioavailability and bioactivity.
Brain/Cognitive Health

Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice.
Cardiovascular

Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week.
Microbiome

Immune effects of cocoa procyanidin oligomers on peripheral blood mononuclear cells.
Biological Effects

Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin.
Cardiovascular

Does flavanol intake influence mortality from nitric oxide-dependent processes? Ischemic heart disease, stroke, diabetes mellitus, and cancer in Panama.
Biological Effects

Cocoa flavanol-enriched snack bars containing phytosterols effectively lower total and low-density lipoprotein cholester
Cardiovascular

Procyanidins protect Caco-2 cells from bile acid- and oxidant-induced damage.