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Columbia University

Columbia University Medical Center (CUMC) offers international leadership in basic, preclinical, and clinical research; medical and health sciences education and patient care. It is home to the largest medical research enterprise in New York City and State and one of the largest faculty medical practices in the Northeast. Mars, Incorporated partnered with scientists at the CUMC to conduct a study published in October 2014, which demonstrated that dietary cocoa flavanols reversed age-related memory decline in healthy, older adults.

Partnership Outcomes

The study, published in Nature Neuroscience with senior author Scott A. Small, MD, provides the first direct evidence that one component of age-related memory decline in humans is caused by changes in a specific region of the brain, the dentate gyrus, and that this form of memory decline can be improved by a dietary intervention. A cocoa flavanol-containing test drink prepared specifically for research purposes was produced by Mars, Incorporated, which partly supported the research, using a proprietary process to extract flavanols from cocoa beans.

Learn More
Read more about the study in the published paper.

Hear from the lead investigator, Scott A. Small, MD of CUMC, about details of the study in this video.