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Biological Effects

Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies
Biological Effects

The metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives
Biological Effects

Vasculoprotective Effects of Dietary Cocoa Flavanols in Patients on Hemodialysis: A Double–Blind, Randomized, Placebo–Controlled Trial
Cardiovascular

Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study
Biological Effects

Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study.
Cardiovascular

Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans.
Reviews

Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs.
Brain/Cognitive Health

The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway.
Cardiovascular

Dose-related effects of flavanol-rich cocoa on blood pressure.
Cardiovascular

Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease.
Cardiovascular

Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease.
Cardiovascular

Impact of cocoa flavanol consumption on blood pressure responsiveness to exercise.
Microbiome

Cocoa flavanols and procyanidins can modulate the lipopolysaccharide activation of polymorphonuclear cells in vitro.
Cardiovascular

Cocoa flavanols lower vascular arginase activity in human endothelial cells in vitro and in erythrocytes in vivo.
Biological Effects

Effect of cocoa flavanols and exercise on cardiometabolic risk factors in overweight and obese subjects.