Published research
Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners
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Cardiovascular
Biomarker-estimated flavan-3-ol intake is associated with lower blood pressure in cross-sectional analysis in EPIC Norfolk
Absorption & Metabolism
Evaluation of (−)-epicatechin metabolites as recovery biomarker of dietary flavan-3-ol intake
Absorption & Metabolism
Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies
Biological Effects
Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies
Biological Effects
The metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives
Biological Effects
Vasculoprotective Effects of Dietary Cocoa Flavanols in Patients on Hemodialysis: A Double–Blind, Randomized, Placebo–Controlled Trial
Cardiovascular
Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study
Cardiovascular
Impact of Cocoa Flavanol Intake On Age-Dependent Vascular Stiffness In Healthy Men: A Randomized, Controlled, Double-masked Trial
Biological Effects
Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study.
Cardiovascular
Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans.
Reviews
Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs.
Brain/Cognitive Health
The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway.
Cardiovascular
Dose-related effects of flavanol-rich cocoa on blood pressure.
Cardiovascular
Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease.
Cardiovascular
