World’s Largest Dietary Intervention Study of Cocoa Flavanols

You are here

Media Type:Video
Title:World’s Largest Dietary Intervention Study of Cocoa Flavanols Investigates Long-Term Cardiovascular Health Benefits
Release Date:May 12, 2015

This randomized placebo-controlled trial, called the COcoa Supplement and Multivitamin Outcomes Study (COSMOS), will enroll 18,000 women and men nationwide, making it the largest dietary intervention study to evaluate the health benefits of cocoa flavanols and a multivitamin. The study is the result of an innovative public-private partnership among BWH, Harvard Medical School, the Seattle-based Fred Hutchinson Cancer Research Center (FHCRC), the National Institutes of Health (NIH), Mars, Incorporated, and Pfizer, Incorporated.

According to JoAnn Manson, MD, Chief of the Division of Preventive Medicine at BWH and co-lead on the study, “The COSMOS trial builds on a decade of scientific evidence indicating that cocoa flavanols improve blood vessel function, metabolic health, and cognition. The depth and breadth of this innovative trial are unprecedented. ”

See the full press release

About Mars Center For Cocoa Health Science

For more than 20 years, and based on collaborating with a multidisciplinary group of international experts, Mars, Incorporated has been conducting comprehensive and innovative research with a network of scientific collaborators around the world to advance the understanding of cocoa flavanols and their health benefits for the purpose of improving human health. Building on decades of research in cocoa flavanols, the Mars Center for Cocoa Health Science (MCCHS) was formally established in 2012 as a Center of Excellence to pioneer, capture and share the latest scientific research in the field. MCCHS provides access to more than 20 years of gold standard research, over 140 published peer-reviewed scientific papers, videos, slides and other information that Mars, Incorporated and its collaborators have developed to advance cocoa flavanol understanding. For more information, please visit Follow us:

About Mars, Incorporated

In 1911, Frank C. Mars made the first Mars candies in his Tacoma, Washington kitchen and established Mars’ first roots as a confectionery company. In the 1920s, Forrest E. Mars, Sr. joined his father in business and together they launched the MILKY WAY® bar. In 1932, Forrest, Sr. moved to the United Kingdom with a dream of building a business based on the objective of creating a “mutuality of benefits for all stakeholders” – this objective serves as the foundation of Mars, Incorporated today. Based in McLean, Virginia, Mars has net sales of more than $33 billion, six business segments including Petcare, Chocolate, Wrigley, Food, Drinks, Symbioscience, and more than 75,000 Associates worldwide that are putting its Principles into action to make a difference for people and the planet through its performance.
For more information, please visit Follow us:,,,


# # #