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Novel insights into the heart health benefits of cocoa flavanols and procyanidins
A new study published today in the American Journal of Clinical Nutrition (AJCN) adds to the body of data demonstrating that bioactive compounds found in cocoa can keep the heart healthy —but two types of bioactives called flavanols and procyanidins behave differently in the body. Bioactives are dietary compounds that can be beneficial to health. Comprised of two kinds of bioactives, namely flavanols and procyanidins, the cocoa flavanols present in cocoa have attracted considerable scientific attention in recent years. As both groups of compounds are also found in apples, grapes, berries, and some cereals and legumes, the use of cocoa extract as a model for flavanol- and procyanidin-containing foods is likely to generate insights relevant beyond cocoa. Multiple studies have shown that daily consumption of flavanols and procyanidins has led to improved blood pressure, cholesterol and the flexibility of blood vessels. But until now, it was less clear to what extent flavanols and procyanidins...
New Film Series Emphasizes Vital Role of Good Nutrition for Healthy Aging
Campaign Launches during National Nutrition Month in March Washington, D.C., March 8, 2016 –Constant exposure to our environment, the things we eat, and stresses from both inside and outside our bodies all cause us to age over time. Although scientists have not yet found a way to delay the biological processes of aging, they are learning more about how healthy behavioral practices, such as maintaining a well-balanced diet, are critical to fostering good health throughout our lives. While eating a nutritious diet overall is essential, the specific amounts and types of nutrients we need and the body’s ability to process them can change with age and with personal health status. During National Nutrition Month, the Alliance for Aging Research, in partnership with the Mars Center for Cocoa Health Science, has released three animated “pocket films” that explain the role of nutrition in healthy aging and highlight some of the latest findings in nutrition research. These pocket films offer an easy...
Cocoa Flavanols Lower Blood Pressure And Increase Blood Vessel Function In Healthy People
New studies by the EU-funded FLAVIOLA research consortium show that cocoa flavanols could help maintain cardiovascular health as we age Dusseldorf, Germany (September 9, 2015) – Two recently published studies in the journals Age and the British Journal of Nutrition (BJN), as a part of the FLAVIOLA project, demonstrate that consuming cocoa flavanols improves cardiovascular function and lessens the burden on the heart that comes with the ageing and stiffening of arteries. The studies also provide novel data to indicate that intake of cocoa flavanols reduces the risk of developing cardiovascular disease (CVD). Cocoa flavanols are plant-derived bioactives from the cacao bean. Earlier studies have demonstrated that cocoa flavanol intake improves the elasticity of blood vessels and lowers blood pressure — but, for the most part, these investigations have focused on high-risk individuals like smokers and people that have already been diagnosed with conditions like hypertension and coronary heart disease...
The Diplomatic Courier And Mars, Incorporated Bring Together Leading Experts To Discuss The “Future Of Food”
150 cross-sector experts, innovators and policymakers will convene today at the National Press Club in Washington, D.C. to drive awareness of the opportunities for collaboration at the nexus of food and health WASHINGTON, D.C. (May 13, 2015) --- The Future of Food: The Nexus of Food and Health summit—co-hosted by global affairs magazine Diplomatic Courier and Mars, Incorporated—will look at the vital role collaboration across sectors can play in sustainably addressing the world’s most pressing food and health challenges. Representatives from organizations as diverse as the UN World Food Programme; the University of California, Davis; and the White House will debate the link between food, health, nutrition and wellness and investigate how a revised, multi-stakeholder approach to policy, research, and innovation can ensure effective impact where it matters most. The world population is expected to rise above nine billion by 2050—meaning food production will need to increase sustainably by up to 70...
World’s Largest Dietary Intervention Study of Cocoa Flavanols Investigates Long-Term Cardiovascular Health Benefits
Ancillary Studies Focus on Potential Benefits of Cocoa Flavanols on Brain Health GERMANTOWN, May 12, 2015 – Recognizing that heart health is one of the world’s most significant public health challenges, Mars, Incorporated, in collaboration with Brigham and Women’s Hospital (BWH), a teaching affiliate of Harvard Medical School, launched a five-year landmark study to examine the role of cocoa flavanols, plant-derived bioactives from the cacao bean, in helping people maintain cardiovascular health. Ancillary studies will focus on a broad range of potential benefits of cocoa flavanols on brain health, including memory, decision-making skills, mood, and cognitive performance, as well as metabolic health. According to JoAnn Manson, MD, Chief of the Division of Preventive Medicine at BWH and co-lead on the study, “The COSMOS trial builds on a decade of scientific evidence indicating that cocoa flavanols improve blood vessel function, metabolic health, and cognition. The depth and breadth of this...
Mounting Evidence Demonstrates Improved Cognitive Function From Cocoa Flavanol Consumption
Mounting Evidence Demonstrates Improved Cognitive Function From Cocoa Flavanol Consumption A study just published in the American Journal of Clinical Nutrition (AJCN) adds to the growing body of evidence demonstrating that cognitive function is improved with a diet high in cocoa flavanols—a group of naturally occurring bioactives found in fresh cocoa beans. More evidence demonstrating that cognitive function is improved with a diet high in cocoa flavanols—a group of naturally occurring bioactives found in fresh cocoa beans. Credit: Mars, Incorporated.   January 6, 2015 / It is normal for cognitive function to slightly deteriorate with age. Memory capacity begins to worsen, along with processing speed and the ability to form long-term memories. Finding a way to defer the onset of these issues becomes increasingly important as life expectancy gets longer and global populations age. This study, conducted by researchers from Italy’s University of L’Aquila and Mars, Incorporated,...
Calithera Biosciences Gains Exclusive, Worldwide License to Mars Symbioscience’s Arginase Inhibitors
Calithera Biosciences Gains Exclusive, Worldwide License to Mars Symbioscience’s Arginase Inhibitors South San Francisco, Calif., Dec.9, 2014 (GLOBE NEWSWIRE)-- Calithera Biosciences, Inc. (NASDAQ:CALA) announced today the signing of an exclusive global license agreement with Mars Symbioscience (“Symbioscience”), a division of Mars, Incorporated, granting Calithera rights to research, develop and commercialize Symbioscience’s portfolio of arginase inhibitors, discovered as part of Mars’ cocoa flavanol research program, for use in human healthcare. Symbioscience’s preclinical arginase inhibitor program will enhance Calithera’s efforts to submit an Investigational New Drug application for an arginase inhibitor with the FDA for the treatment of cancer near the end of 2015. "We believe that drugs targeting immuno-oncology and tumor metabolism pathways have the potential to be transformational in the treatment of cancer, and at Calithera, we are dedicated to researching and developing potential first-in...
Taking Cocoa Flavanols Can Reverse Memory Decline As We Age
NEW YORK, NY (October 26, 2014)—Dietary cocoa flavanols—naturally occurring bioactives found in cocoa—reversed age-related memory decline in healthy older adults, according to a study led by Columbia University Medical Center (CUMC) scientists. The study, published today in the advance online issue of Nature Neuroscience, provides the first direct evidence that one component of age-related memory decline in humans is caused by changes in a specific region of the brain and that this form of memory decline can be improved by a dietary intervention. As people age, they typically show some decline in cognitive abilities, including learning and remembering such things as the names of new acquaintances or where they parked the car or placed their keys. This normal age-related memory decline starts in early adulthood but usually does not have any noticeable impact on quality of life until people reach their fifties or sixties. Age-related memory decline is different from the often-devastating memory impairment...
Mars, Incorporated Encourages Young Researchers To Cross Disciplinary Boundaries And Help Address The Challenges Of Aging Research At Nobel Laureate Gathering
Nobel Laureate, Prof. Elizabeth Blackburn; Mars Director of Fundamental Health and Nutrition research, Dr. Hagen Schroeter, and 150 of the world’s brightest medical researchers take part in key panel discussion on aging and health Lindau, Germany (July 3, 2014) --- At the 64th Lindau Nobel Laureate Meeting, Nobel Laureate Prof. Elizabeth Blackburn and Dr. Hagen Schroeter, Director of Fundamental Health and Nutrition Research at Mars, Incorporated, explored how current approaches to aging research could be advanced by strengthening the connections between disciplines, sectors and stakeholders. The panel engaged an audience of 100 of the world's brightest young researchers, and considered how to integrate a broad range of scientific fields more effectively in order to tackle the challenge of healthy aging. At the panel discussion, Hagen Schroeter spoke about his experience of convergent research: “Integrating insights from distinct disciplines and across sectors has greatly benefitted Mars, Incorporated’...
Largest Nutritional Intervention Trial of Cocoa Flavanols And Hearth Health To Be Launched
Study brings together academia, industry and the National Institutes of Health BOSTON, Ma. – In a novel collaboration, Brigham and Women’s Hospital, the Seattle-based Fred Hutchinson Cancer Research Center, the National Institutes of Health (NIH), and Mars, Incorporated plan to partner on the largest research trial to date investigating the health benefits of cocoa flavanols. Once initiated, this large-scale, prospective nutritional intervention will evaluate the role of flavanols in reducing the risk of heart attack, stroke, and death from cardiovascular disease. Flavanols are naturally occurring plant-derived bioactive compounds in a variety of food sources. The study will also explore the effect of a daily multivitamin as compared to placebo, as a follow up to previous research conducted only in men which suggested that multivitamins may lower the risk of cancer. This five-year study will also be the first large-scale randomized trial testing multivitamins in women. “Cocoa flavanols and...