Published research
Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners
All ResearchAll Research
Absorption & MetabolismAbsorption & Metabolism Analytical MethodsAnalytical Methods Biological EffectsBiological Effects Brain/Cognitive HealthBrain/Cognitive Health CardiovascularCardiovascular ChemistryChemistry History of Cocoa FlavanolsHistory of Cocoa Flavanols MicrobiomeMicrobiome Other Biological EffectsOther Biological Effects ReviewsReviews
Cardiovascular
Biomarker-estimated flavan-3-ol intake is associated with lower blood pressure in cross-sectional analysis in EPIC Norfolk
Analytical Methods
Reliable, accessible and transferable method for the quantification of flavanols and procyanidins in foodstuffs and dietary supplements†
Absorption & Metabolism
Evaluation of (−)-epicatechin metabolites as recovery biomarker of dietary flavan-3-ol intake
Absorption & Metabolism
Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies
Analytical Methods
Use of LC-MS for the quantitative analysis of (poly)phenol metabolites does not necessarily yield accurate results: Implications for assessing existing data and conducting future research.
Reviews
Absorption, metabolism, distribution and excretion of (-)-epicatechin: A review of recent findings.
Biological Effects
Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies
Biological Effects
The metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives
Biological Effects
Vasculoprotective Effects of Dietary Cocoa Flavanols in Patients on Hemodialysis: A Double–Blind, Randomized, Placebo–Controlled Trial
Biological Effects
Safety And Efficacy of Cocoa Flavanol Intake In Healthy Adults: A Randomized, Controlled, Double-masked Trial
Cardiovascular
Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study
Cardiovascular
Impact of Cocoa Flavanol Intake On Age-Dependent Vascular Stiffness In Healthy Men: A Randomized, Controlled, Double-masked Trial
Chemistry
Total Synthesis of Proanthocyanidin A1, A2, and Their Stereoisomers
Brain/Cognitive Health
Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study—a randomized controlled trial
Brain/Cognitive Health
