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The Cocoa Flavanol Science Blog

Published research

Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners

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Cardiovascular

Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans.
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The American Journal of Clinical Nutrition logo View Abstract
Analytical Methods

Structurally related (-)-epicatechin metabolites in humans: assessment using de novo chemically synthesized authentic standards.
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Biological Effects

Selective removal of the violet color produced by anthocyanins in procyanidin-rich unfermented cocoa extracts.
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Journal of Food Science logo View Abstract
Analytical Methods

Physicochemical properties of acidified skim milk gels containing cocoa flavanols.
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Journal of Agriculture and Food Chemistry logo View Abstract
Chemistry

The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo.
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Microbiome

Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, double-blind, crossover intervention study.
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The American Journal of Clinical Nutrition logo View Abstract
Reviews

Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs.
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Brain/Cognitive Health

The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway.
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Brain/Cognitive Health

Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort.
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British Association for Psychopharmacology logo View Abstract
Cardiovascular

Dose-related effects of flavanol-rich cocoa on blood pressure.
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Journal of Human Hypertension logo View Abstract
Chemistry

Enantioselective syntheses of sulfur analogues of flavan-3-Ols.
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Molecules logo View Abstract
Chemistry

Synthesis of [2-13C, 4-13C]-(2R,3S)-catechin and [2-13C, 4-13C]-(2R,3R)-epicatechin
Journal of Labelled Compounds and Radiopharmaceuticals logo View Abstract
Cardiovascular

Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease.
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Journal of the American College of Cardiology logo View Abstract
Cardiovascular

Impact of cocoa flavanol consumption on blood pressure responsiveness to exercise.
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British Journal of Nutrition logo View Abstract
Biological Effects

Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity.
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Society for Experimental Biology and Medicine logo View Abstract