Dietary Cocoa Flavanols Improve Vascular Function in Patients with Kidney Dysfunction

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Thursday, December 17, 2015

Washington, DC – A dietary intervention study published today in the Clinical Journal of the American Society of Nephrology (CJASN) demonstrates that the daily intake of cocoa flavanols could significantly improve vascular function and reduce diastolic blood pressure in kidney patients on chronic hemodialysis. Patients undergoing chronic hemodialysis were randomized to receive either a beverage containing a standardized amount of cocoa flavanols (450 mg per serving), bioactive compounds extracted from cocoa beans (provided by Mars Symbioscience), or a nutrient-matched control test drink containing no cocoa flavanols. The study participants consumed the assigned drink twice daily for 30 days. After 30 days, the group consuming 900 mg of cocoa flavanols daily had significantly improved blood vessel function and reduced diastolic blood pressure. This study suggests that cocoa flavanols may be one dietary approach for improving cardiovascular-related health outcomes in patients with kidney dysfunction undergoing hemodialysis.

Clinical Journal of the American Society of Nephrology (CJASN)

About Mars Center For Cocoa Health Science

For more than 20 years, and based on collaborating with a multidisciplinary group of international experts, Mars, Incorporated has been conducting comprehensive and innovative research with a network of scientific collaborators around the world to advance the understanding of cocoa flavanols and their health benefits for the purpose of improving human health. Building on decades of research in cocoa flavanols, the Mars Center for Cocoa Health Science (MCCHS) was formally established in 2012 as a Center of Excellence to pioneer, capture and share the latest scientific research in the field. MCCHS provides access to more than 20 years of gold standard research, over 140 published peer-reviewed scientific papers, videos, slides and other information that Mars, Incorporated and its collaborators have developed to advance cocoa flavanol understanding. For more information, please visit Follow us:

About Mars, Incorporated

In 1911, Frank C. Mars made the first Mars candies in his Tacoma, Washington kitchen and established Mars’ first roots as a confectionery company. In the 1920s, Forrest E. Mars, Sr. joined his father in business and together they launched the MILKY WAY® bar. In 1932, Forrest, Sr. moved to the United Kingdom with a dream of building a business based on the objective of creating a “mutuality of benefits for all stakeholders” – this objective serves as the foundation of Mars, Incorporated today. Based in McLean, Virginia, Mars has net sales of more than $33 billion, six business segments including Petcare, Chocolate, Wrigley, Food, Drinks, Symbioscience, and more than 75,000 Associates worldwide that are putting its Principles into action to make a difference for people and the planet through its performance.
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