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The COSMOS Trial

While cocoa flavanols have been studied for over 20 years, by Mars and by others, there is still more to uncover about the benefits of these bioactives to human health. There is significant research underway, including COSMOS, the largest study yet into the cardiovascular benefits of flavanols.

COSMOS stands for the Cocoa Supplement and Multivitamin Outcomes Study. It is a randomized, double-blinded, and placebo-controlled trial and brings together multiple leading medical research institutions. Partners include: Brigham and Women’s Hospital; Harvard Medical School; Fred Hutchinson Cancer Research Center; the National Institutes of Health; and Mars, Incorporated.

The study began in 2015 with over 21,000 men and women from across the Unites States participating. Researchers are assessing if the daily intake of cocoa flavanols reduces the risk of developing a range of health issues, including heart attack, stroke, cardiovascular disease, cancer. COSMOS will conclude in 2020, with results expected in 2021.

Learn more about COSMOS at